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Clinical trials for Cardiac Care

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,058 result(s) found for: Cardiac Care. Displaying page 1 of 53.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2019-001995-12 Sponsor Protocol Number: CCM1006 Start Date*: 2019-09-27
    Sponsor Name:CENTRO CARDIOLOGICO SPA FONDAZIONE MONZINO
    Full Title: Cardiac Arrhythmia catheter ablation procedures guided by x-Ray imaging: N-Acetylcysteine Protection Against radiation induced Cellular damagE (CARAPACE Study).
    Medical condition: Patients with Cardiac Arrhythmia who undergo catheter ablation procedures guided by x-Ray imaging
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004849 10007518 Cardiac arrhythmia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000972-40 Sponsor Protocol Number: MK-6621-055 Start Date*: 2012-08-20
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Multicentered, Randomized, Open-Label, Pragmatic Use Study Comparing Vernakalant Therapy to Amiodarone Therapy in Acute Management of Recent Onset Atrial Fibrillation.
    Medical condition: Atrial Fibrilation
    Disease: Version SOC Term Classification Code Term Level
    15.0 10007541 - Cardiac disorders 10007545 Cardiac dysrhythmias LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004773-13 Sponsor Protocol Number: 00001 Start Date*: 2018-02-27
    Sponsor Name:Research Center for Emergency Medicine Department of Clinical Medicine Aarhus University
    Full Title: Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest – A Randomized, Double-Blind, Placebo-Controlled Trial
    Medical condition: The study will include patients with in-hospital cardiac arrest (IHCA). The study will test whether treatment with methylprednisolone and vasopressin added to standard care will improve survival fo...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007515 Cardiac arrest PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-013066-31 Sponsor Protocol Number: HSR-LEVO Start Date*: 2009-07-31
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: “Levosimendan to reduce mortality in high risk cardiac surgery patients. A multicentre randomized controlled trial.”
    Medical condition: high risk cardiac surgery affected by low cardiac output syndrome (LCOs)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-021263-33 Sponsor Protocol Number: 3001101 Start Date*: 2011-05-24
    Sponsor Name:Sykehuset i Vestfold HF
    Full Title: PERIOPERATIVE LEVOSIMENDAN INFUSION IN PATIENTS WITH HEART FAILURE UNDERGOING NON-CARDIAC SURGERY: A PROSPECTIVE, RANDOMISED, PLACEBO-CONTROLLED, DOUBLE-BLIND, MULTICENTER STUDY
    Medical condition: Patients with serious cardiac failure scheduled for non-cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10006387 Broken hip LLT
    14.1 10007541 - Cardiac disorders 10007559 Cardiac failure congestive PT
    14.1 10007541 - Cardiac disorders 10007554 Cardiac failure PT
    14.1 10007541 - Cardiac disorders 10066498 Cardiac failure chronic aggravated LLT
    14.1 10007541 - Cardiac disorders 10007558 Cardiac failure chronic PT
    14.1 10007541 - Cardiac disorders 10024102 Left cardiac failure LLT
    14.1 10007541 - Cardiac disorders 10007561 Cardiac failure left LLT
    14.1 10007541 - Cardiac disorders 10007555 Cardiac failure (NOS) LLT
    14.1 10007541 - Cardiac disorders 10007564 Cardiac failure, congestive LLT
    14.1 10007541 - Cardiac disorders 10007562 Cardiac failure NOS LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10020100 Hip fracture PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-000792-11 Sponsor Protocol Number: Start Date*: 2014-07-09
    Sponsor Name:University of Warwick
    Full Title: Prehospital Assessment of the Role of Adrenaline: Measuring the Effectiveness of Drug administration In Cardiac arrest
    Medical condition: Out of hospital cardiac arrest
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002208-14 Sponsor Protocol Number: Protocol v.1.2 30/08/04 Start Date*: 2005-02-21
    Sponsor Name:Cardiff and Vale NHS Trust
    Full Title: Duration of Amiodarone therapy required for new post cardiac surgery atrial fibrillation.
    Medical condition: Atrial fibrillation following cardiac surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-004311-45 Sponsor Protocol Number: 2013-PharmaCA-001 Start Date*: 2014-03-25
    Sponsor Name:Copenhagen University Hospital Rigshospitalet, Department of Cardiology B 2143
    Full Title: GLP-1 ANALOGS FOR NEUROPROTECTION AFTER OUT-OF-HOSPITAL CARDIAC ARREST, A RANDOMIZED CLINICAL TRIAL
    Medical condition: We investigate the efficacy of commercially available GLP-1 analog for reducing post anoxic brain injury in patients who remain comatose after having been resuscitation from out of hospital cardiac...
    Disease: Version SOC Term Classification Code Term Level
    17.0 10007541 - Cardiac disorders 10007515 Cardiac arrest PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-000473-20 Sponsor Protocol Number: CLCZ696B3402 Start Date*: 2016-08-18
    Sponsor Name:Novartis Pharma services AG
    Full Title: A prospective evaluation of natriuretic peptide based referral of CHF patients in primary care
    Medical condition: Chronic heart failure with reduced ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-001285-15 Sponsor Protocol Number: KOIIM-2019-1 Start Date*: 2019-06-28
    Sponsor Name:University Medical Centre Ljubljana
    Full Title: Platelet inhibition with cangrelor in comatose survivors of out-of-hospital cardiac arrest undergoing primary percutaneous coronary intervention
    Medical condition: Comatose survivors of out-of-hospital cardiac arrest undergoing primary percutaneous coronary intervention
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-007287-42 Sponsor Protocol Number: IVA-TCMD Start Date*: 2009-04-17
    Sponsor Name:AZIENDA OSPEDALIERA DI PARMA
    Full Title: Ivabradine in multislice CT: comparison with metoprolol in the reduction of motion artefacts and in the improvement of diagnostic care.
    Medical condition: patients with coronary arteries desease, who need Tc multislice for diagnostic reasons
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-016958-41 Sponsor Protocol Number: FO002 Start Date*: 2010-02-28
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA` GRANDA (A.O. DI RILIEVO NAZIONALE)
    Full Title: Early LEvosimendan Vs usual care in Advanced chronic hearT failurE
    Medical condition: Advanced chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-003797-23 Sponsor Protocol Number: KKS-305 Start Date*: 2023-05-16
    Sponsor Name:Philipps University Marburg
    Full Title: Myeloperoxidase inhibition in patients with ischemic or non-ischemic cardiomyopathy and heart failure with reduced ejection fraction
    Medical condition: Ischemic or non-ischemic cardiomyopathy and heart failure with reduced ejection fraction. Danke
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007554 Cardiac failure PT
    26.1 10007541 - Cardiac disorders 10078289 Heart failure with reduced ejection fraction LLT
    20.0 10007541 - Cardiac disorders 10055222 Non-ischemic cardiomyopathy LLT
    20.0 10007541 - Cardiac disorders 10055217 Ischemic cardiomyopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003088-87 Sponsor Protocol Number: WWU20_0016 Start Date*: 2021-11-22
    Sponsor Name:Westfälische Wilhelms-Universität Münster
    Full Title: Biomarker-guided implementation of angiotensin-II (AT-II) to reduce the occurrence of kidney damage after cardiac surgery
    Medical condition: Cardiac surgical patients at high risk for AKI
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    20.1 10038359 - Renal and urinary disorders 10080266 Stage 1 acute kidney injury LLT
    20.1 10038359 - Renal and urinary disorders 10080269 Stage 2 acute kidney injury LLT
    20.1 10038359 - Renal and urinary disorders 10080271 Stage 3 acute kidney injury LLT
    20.0 100000004863 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: View results
    EudraCT Number: 2021-005922-82 Sponsor Protocol Number: IVIO1.3 Start Date*: 2022-01-13
    Sponsor Name:Prehospital Emergency Medical Services, Central Denmark Region
    Full Title: Intravenous vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest - A Randomized Clinical Trial
    Medical condition: Out-of-hospital cardiac arrest (OHCA)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10007517 Cardiac arrest transient LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-003053-24 Sponsor Protocol Number: 614 Start Date*: 2006-05-18
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Prophylaxis with fenoldopam in cardiac surgery patients at high risk of postoperative renal failure
    Medical condition: cardiac surgery patients at high risk of postoperative renal failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007593 Cardiac therapeutic procedures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002366-23 Sponsor Protocol Number: AD-V1-05252015 Start Date*: 2015-10-13
    Sponsor Name:Medical University of Vienna, Department of Anaesthesia, General Intensive Care and Pain Management
    Full Title: Goal-directed heart rate control during emergence from anesthesia using esmolol to attenuate myocardial injury in patients undergoing non-cardiac surgery
    Medical condition: myocardial damage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-001809-50 Sponsor Protocol Number: C3651011 Start Date*: 2023-01-27
    Sponsor Name:Pfizer Inc.
    Full Title: A PHASE 2, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, 4-ARM STUDY TO INVESTIGATE SYMPTOMS, FUNCTION, HEALTH-RELATED QUALITY OF LIFE AND SAFETY WITH REPEATED SUBCUTANEOUS ADMINISTRATION OF PONSEG...
    Medical condition: Heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) DE (Trial now transitioned) HU (Trial now transitioned) PL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002873-80 Sponsor Protocol Number: AMILCA-DIFLU Start Date*: 2020-01-14
    Sponsor Name:FUNDACION JIMENEZ DIAZ HEALTH RESEARCH INSTITUTE
    Full Title: Unicentre, open, uncontrolled clinical trial to assess the morphological, biochemical and functional effects of Diflunisal treatment in patients with transthyretin cardiac amyloidosis
    Medical condition: transthyretin cardiac amyloidosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000087-26 Sponsor Protocol Number: 2019/09 Start Date*: 2020-04-16
    Sponsor Name:CMC AMBROISE PARE
    Full Title: Time to transit Recovery After treatment with Naloxegol in cardiac Surgery Intensive care Trial
    Medical condition: ileus after cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10017501 Functional disturbances following cardiac surgery LLT
    20.1 100000004863 10051798 Postoperative constipation LLT
    20.0 100000004856 10071128 Opioid induced constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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